{"id":1326,"date":"2023-08-16T11:56:27","date_gmt":"2023-08-16T14:56:27","guid":{"rendered":"https:\/\/cestodos.fcien.edu.uy\/?post_type=avada_portfolio&p=1326"},"modified":"2023-08-16T11:56:27","modified_gmt":"2023-08-16T14:56:27","slug":"organization-and-composition-of-the-tegument","status":"publish","type":"avada_portfolio","link":"https:\/\/cestodos.fcien.edu.uy\/?avada_portfolio=organization-and-composition-of-the-tegument&lang=en","title":{"rendered":"Organization and composition of the tegument"},"content":{"rendered":"

Organization and composition of the tegument<\/strong><\/h3><\/div>

Unlike most animals, parasitic flatworms are covered by a syncytial tegument (a giant cell with many nuclei) instead of a typical epidermis. All interactions between cestodes and their hosts occur through the tegument, including the absorption of nutrients, since these parasites lack a digestive system.<\/span><\/p>\n<\/div>

<\/div>

The tegument has an outer, superficial part that covers the parasite, which is connected to cell bodies in the interior where the nuclei are located. All new tegumental proteins are synthesized in the cell bodies and must be transported to the surface. We study the identity of these proteins, and how they are transported within the tegument. Furthermore, we study the effect of antiparasitic drugs in these processes.<\/span><\/p>\n<\/div>

<\/span><\/div>

\u00abDistribuci\u00f3n del citoesqueleto de microt\u00fabulos (naranja) y<\/h4>\n

de actina (verde) en el tegumento de Mesocestoides corti\u00bb<\/h4>\n<\/div><\/div><\/div>

Funding:\u00a0<\/span><\/p>\n

PROYECTO ANII Fondo Clemente Estable 2019: <\/span>Organizaci\u00f3n y tr\u00e1fico intracelular en el tegumento de cestodos: roles del citoesqueleto de microt\u00fabulos. <\/span><\/i>(Responsable: Uriel Koziol)<\/span><\/p>\n

PROYECTO ANII Fondo Clemente Estable 2021: <\/span>Prote\u00f3mica comparativa y mecanismos de reparaci\u00f3n del tegumento de cestodos, una estructura esencial en la interacci\u00f3n hospedero-par\u00e1sito. <\/span><\/i>(Responsable: Uriel Koziol)<\/span><\/p>\n<\/div>

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